【问题】 ScientistsatUniversityCollegeLondonhavediscoveredsetsofregulatorygenes,whichareresponsibleformaintaininghealthyhearing.Thefinding,madeinfruitflies,couldleadtotreatmentsforage-relatedhearingloss(ARHL)inhumans. Globally,one-thirdofpeopleagedover65experience

ScientistsatUniversityCollegeLondonhavediscoveredsetsofregulatorygenes,whichareresponsibleformaintaininghealthyhearing.Thefinding,madeinfruitflies,couldleadtotreatmentsforage-relatedhearingloss(ARHL)inhumans. Globally,one-thirdofpeopleagedover65experiencehearingimpairment,andwhiletherearethoughttobemorethan150genesthatmayaffecthearingloss,thereisnounifiedviewonhowtousethesetodevelophearinglosstreatments. Inthestudy,publishedinScientificReports,researchersattheUCLEarInstituteassessedthehearingabilityofthecommonfruitflyacrossitslifespan(around70days)toseeiftheirhearingdeclineswithage. Afruitfly'searssharemanymolecularsimilaritieswiththeearsofhumans,makingitanidealtoolforthestudyofhumanhearingloss. ResearchersfoundthattheantennalearsoffruitfliesalsodisplayARHLwithnearlyallsensitivehearingmeasuresstartingtodeclineafter50daysofage.Thismadetheresearcherswanttoknowiftherewereany"age-variable"genesintheflies'innerearswhichhavekepttheearshealthyfor50daysoftheirlives. Aftercloserexamination,researchersidentifiedanewsetofregulatorygenes-homeostasisgenes.Thesegenesareoftenresponsibleforpickingupsoundandtheoverallsensitivityoftheear.Usingthisinformation,scientistswerethenabletogeneticallymodifythegenesandpreventthefliesfromgettingARHL. ProfessorJoergAlbert,leadauthorofthestudy,said:"Whilemanystudieshavebeenconductedintothehearingfunctionoffruitflies,oursisthefirsttolookatthemechanisticandmoleculardetailoftheirauditorylifecourse." "Thefactthatthesegenesareconservedinhumanswillalsohelptofocusfutureclinicalresearchinhumansandtherebyacceleratethediscoveryofnewpharmacologicalorgene-therapeuticstrategies."(1)WhatdidscientistsatUCLdiscover?______A.Homeostasisgenesmaintainone'sabilitytohear.B.One-thirdofpeopleagedover65havehearingproblems.C.Thereareregulatorygenesthatarerelatedtoaging.D.Humanshaveover150genesthatcanaffecthearingloss.(2)Whywerefruitfliesusedintheresearch?______A.Theysharemanygeneswithhumans.B.TheydisplayARHLduringtheirlifespan.C.Theirhearingabilityalsodeclineswithage.D.Theirhearingsystemissimilartothatofhumans'.(3)Whatisthemainpurposeofthelasttwoparagraphs?______A.Thediscoveryofnewtreatments.B.Thesignificanceofthestudy.C.Theresultofthestudy.D.Thefuturecommercialprospects.(4)Whichofthefollowingwouldbethebesttitleforthetext?______A.Age-relatedhearingloss:fruitfliesandhumansB.Hearingloss:acommonproblemforolderadultsC.GenediscoverycouldleadtohearinglosstreatmentsD.Thebody'sabilitycanbeunlockedtotreatlosthearing

正确答案:(1)A.细节理解题。根据第六段"After closer examination,researchers identified a new set of regulatory genes-homeostasis genes. These genes are often responsible for picking up sound and the overall sensitivity of the ear. "(经过更仔细的研究,研究人员发现了一组新的调节基因--稳态基因。这些基因通常负责

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本文是一篇说明文。文章主要介绍了对果蝇听觉系统的研究,该研究可以为人类听力丧失治疗提供治疗策略。

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